BONES, JOINT &
INFLAMMATION
As the body ages, many people experience joint discomfort. One option is to take a joint supplement to help promote overall bone and joint health. When looking at a joint supplement,
there are three main ingredients found in most products on the market: glucosamine, chondroitin and methylsulfonylmethane, more commonly referred to as MSM.The research on both
chondroitin and MSM is very controversial. Chondroitin, for instance, has very poor absorption due to its high molecular weight. Also, one of chondroitin’s mechanisms is to increase the
hyaluronic acid content of synovial fluid; while the new Prime Joint Support Formula by Isotonix directly provides hyaluronic acid. Hyaluronic acid plays an important role in tissue hydration,
lubrication and cellular function. Likewise, research on MSM is not conclusive. In fact, it takes large quantities of MSM daily (2-6 grams) to make a difference and see effects.*On the other
hand, the research behind glucosamine is consistent and its benefits effective. Prime Joint Support Formula contains glucosamine, naturally produced by the body and a key component of
cartilage. An aminomonosaccharide (a combination of the amino acid — glutamine and a sugar — glucose), glucosamine is concentrated in joint cartilage, and has been scientifically
proven to support healthy joint function and promote the normal production of synovial fluid, which lubricates your joints and regenerates cartilage.* Prime Joint Support Formula also
contains the powerful antioxidant Pycnogenol®, which science has shown to inhibit the body’s over-active inflammatory processes associated with the normal aging process.The body’s
inflammatory response is a natural process. It is an essential component of the body’s defense system, and can be triggered from numerous internal and external factors. Pycnogenol has
been shown help support the body’s defense system by inhibiting over active inflammatory responses associated with the normal aging process. To learn more the relationship between
Pycnogenol and joint health, click the links below to access the full text studies.http://www.pycnogenol.com/pdf/Pycnogenolforjointhealth.pdfhttp://www.ncbi.nlm.nih.
gov/pubmed/19508901http://www.ncbi.nlm.nih.gov/pubmed/16441890Furthermore, Prime Joint Support Formula is the only product on the market delivering glucosamine, Pycnogenol and
hyaluronic acid in isotonic form.*Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain
concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be
absorbed and used in the body’s metabolism, it must be in an isotonic state.Isotonix® dietary supplements are delivered in an isotonic solution. This means that the body has less work to
do to obtain maximum absorption of the nutrients. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and rapidly absorb into the bloodstream. With
Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.

Benefits:

Our EXCLUSIVE SOLUTION for promoting optimal joint health and for bone & joint discomfort
Only product on the market delivering glucosamine, Pycnogenol and hyaluronic acid in isotonic form.
This winning combination of proven ingredients preserves optimal joint health by maintaining your joints’ optimal fluidity and flexibility:
Glucosamine - Supports ealthy joint function and promotes the normal production of synovial fluid, which lubricates your joints and regenerates cartilage
Pycnogenol® - Inhibits the body’s overactive inflammatory processes & supports relief from temporary inflammation associated with daily activities and the normal aging process
Hyaluronic Acid - Helps maintain strong, healthy cartilage and promotes normal healing
Additional Benefits -
Keep your joints young
Helps maintain joint comfort
Supports normal, healthy levels of COX-2 and 5-LOX
Contains the combination of glucosamine with the super powerful antioxidantPycnogenol® and hyaluronic acid
Does not contain chondroitin (very poor absorption due to its high molecular weight)

INGREDIENTS:
Glucosamine (HCl) 1000 mg
Glucosamine is a molecule that is naturally synthesized in the body from glucose and the amino acid glutamine. Glucosamine is an important constituent of glycosaminoglycans in cartilage
matrix and synovial fluid. As our bodies age, we are less able to produce glucosamine, resulting in cartilage that is less flexible and weak. Although the mechanism is currently unclear,
studies have shown that glucosamine supplementation can support normal, healthy cartilage cell production to help maintain overall joint health.

Pine Bark Extract (Pycnogenol®) 25 mg
Pycnogenol is a water-soluble, flavonoid complex with powerful benefits. Pycnogenol, similar to the proanthocyanins found in grape seeds, is extracted from the bark of the French maritime
pine tree. Numerous studies have examined the anti-inflammatory properties of Pycnogenol.

The body’s inflammatory response is a natural process. It is an essential component of the body’s defense system, and can be triggered from numerous internal and external factors.
Pycnogenol has been shown help maintain the body’s natural defenses by inhibiting over active inflammatory responses associated with the normal aging process. Research has shown
that Pycnogenol may inhibit the activation of NF-kappa B and AP-1, both of which are proinflammatory mediators. Pycnogenol supplementation can also promote normal COX-2 and 5-LOX
gene expression, and support healthy leukotriene biosynthesis. In addition, studies have shown the ability of Pycnogenol to cross-link collagen fibers and strengthen connective tissue
proteins.

Hyaluronic Acid (Sodium Hyaluronate) 25 mg
Hyaluronic acid plays an important role in tissue hydration, lubrication and cellular function. Although it is produced naturally by the body, the level of hyaluronic acid diminishes with age,
contributing to joint discomfort. It is a key component of cartilage, and is important for skin, joint and eye health. Hyaluronic acid has been shown to help maintain strong, healthy cartilage. It
may also enhance synovial fluid production and promote normal healing.
BONE & JOINT FORMULA